A brief history of toxicology testing on animals /11

2. The numbers game: how animal-based toxicological risk assessment works
The US National Toxicological program /19 
Toxicological risk assessment: a brief overview /20 
How the NTP animal testing program works /21 
The species and numbers of animals used in toxicity tests /21
How animal testing is performed /24 
How animal data are extrapolated to humans /27 
How animal data are used within the regulatory framework /28

3. For the public good? Debunking the animal testing myth
The arguments in favor of animal testing /44 
The arguments against /49 
The difficulty of inter-species extrapolation /50 
False positives/false negatives /57 
Different testing methods produce different results /60 
The artificiality of laboratory life /64 
Humans make mistakes /68 
The animal tests have never been validated /69 
A criticism of specific tests and methods /74 
Humanitarian considerations /78 
Time and cost of testing /84

4. Human health at risk
Criticism of the risk assessment process /103 
Getting away with murder /106 
Why animal tests do not protect humans from toxins /109 
Particular chemicals as examples /112 
The laws and guidelines governing animal testing requirements /122  The business of animal testing: who profits? /131

5. Toxicological testing without using animals
The alternatives concept /153 
Examples of non-animal toxicological testing methods /152 
The 'alternatives' scam: refinement and reduction vs. full replacement /168 
The validation issue: a barrier to a full and immediate ban on animal testing /179 
Some success stories /186

6. Reclaiming our health and our humanity: strategies for change
The need for a new paradigm /209  Chemical bans /214 
The path to revolution: forms of public protest /217 
The activist struggle in the face of economic globalization /219 
Environmentalists and animal advocates: a necessary union /220 
Legislation /222 
The False Claims Act: a legal challenge to the the US government /223  The future of toxicity testing without animals /225

To help avoid this unnecessary and worthless orgy of animal testing that will result in millions of animals dying painful deaths, your letters are needed to:

Vice President Al Gore
Old Executive Office Building
Washington DC 20601

Carol M Browner, EPA
401 M Street SW
Washington DC 200460               Fax 202-260-0279

Fred Krupp, Executive director
Environmental Defense Fund
257 Park Avenue South
New York NY 10010                       Fax 212-205-2375

Frederick L. lWebber, President
Chemical Manufacturers Association
1300 Wilson Boulevard
Arlington VA                                     Fax 703-741-6000

Dr Gerald Pflug, President
Soap and Toiletry Association
475 Park Avenue South
New York NY 10018                        Fax 212-213-1685

VVV

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